Pre-Clinical Testing of eSVS Mesh
The eSVS Mesh has been studied in a number of animal models to confirm performance expectations. These studies showed a statistically significant inhibition of intimal hyperplasia when the eSVS Mesh was used in CABG procedures. Preclinical studies utilizing the eSVS Mesh technology have been published in peer-reviewed journals including The Journal of Vascular Surgery (June 20091 and November 20112), The European Journal of Cardio-Thoracic Surgery (January 20133) and Innovations (Jan-Feb 20134).
1 Zilla P, Wolf MF, Rafiee N, et al. Utilization of shape memory in external vein-graft meshes allows extreme diameter constriction for suppressing intimal hyperplasia: a non-human primate study. J Vasc Surg. 2009 Jun; 49(6):1532-42.
2 Zilla P, Moodley L, Wolf MF, et al. Knitted nitinol represents a new generation of constrictive external vein graft meshes. J Vasc Surg. 2011 Nov; 54(5):1439-50.
3 Moodley L, Franz T, Human P, et al. Protective constriction of coronary vein grafts with knitted nitinol. Eur J Cardiothorac Surg 2013 Jul; 44(1):64-71.
4 Emery RW and Solien E. Intraoperative transit-time flow measurement is not altered in venous bypass grafts covered by the eSVS Mesh. Innovations (Phila) 2013 Jan-Feb;8(1):37-41.
2 Zilla P, Moodley L, Wolf MF, et al. Knitted nitinol represents a new generation of constrictive external vein graft meshes. J Vasc Surg. 2011 Nov; 54(5):1439-50.
3 Moodley L, Franz T, Human P, et al. Protective constriction of coronary vein grafts with knitted nitinol. Eur J Cardiothorac Surg 2013 Jul; 44(1):64-71.
4 Emery RW and Solien E. Intraoperative transit-time flow measurement is not altered in venous bypass grafts covered by the eSVS Mesh. Innovations (Phila) 2013 Jan-Feb;8(1):37-41.